Turning DNA analysis into an open competition
GenotypeNet transforms variant calling—the foundational layer of genomics—into a public proving ground where anyone can compete.
We create realistic genome challenges. Validators score submissions using established benchmarking standards. Everything is public — it's clear what works, what doesn't, and how methods truly compare and improve over time.
How it works
Synthetic Genomes
Cryptographically uniqueWe generate genomes with carefully selected, biologically plausible mutations, unique to each round. ~3.2 billion positions—impossible to game.
Gold-Standard Truth Genotypes
Validators know ground truthEach task is randomized and truth-checked. Only real genomic algorithms can win.
Run Your Pipeline
Any tool, any approachMiners download the task, run any tools they choose, and submit their algorithms.
Automated Scoring
hap.py standardValidators compare calls to truth using industry-standard benchmarking and publish scores.
Open Competition
Results speakOpen-source scoring creates a fair proving ground. Best methods rise to the top.
Why it matters
The Foundation
Variant calling is the foundational step. Everything downstream depends on this.
Real Impact
Better calls enable clearer diagnostics and faster research.
Honest Progress
Public scoring keeps evaluation honest. No cherry-picked benchmarks.
Who it's for
Ready to compete?
Join the subnet, run your algorithm, and watch your performance go live.